Pregnancy · Digestive
Acid Reflux in Pregnancy
Heartburn shows up for ~50% of pregnancies, especially in the third trimester. These are the OB-cleared first lines.
Reviewed Apr 2026 by Nadia, PharmD
Common symptoms
- Burning after meals
- Worse lying down
- Third-trimester reflux
- Nighttime symptoms
What pharmacists reach for
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After-meal relief
Calcium carbonate and alginate-based antacids are first-line in pregnancy — neither is meaningfully absorbed. Skip sodium bicarbonate and bismuth.
Quick guide
When to talk to a pro
- Symptoms haven't improved after 7 days of consistent use.
- Your baby is under 3 months old — always loop in your pediatrician.
- You spot bleeding, fever, or sudden swelling.
- You're on prescription meds and want to check for interactions.